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Patient recruitment, enrollment, and retention are significant elements of clinical trial programs. Recruiting and retaining the ideal patients at the right time is critical for producing an accurate database for scientific and regulatory purposes. If not, it can cause the development timetable to be extended by many years. To optimise both, you must have a strategy and successfully employ analytics and technology while keeping the participant's user experience in mind. The demands of patient groups, the relevance of diversity, the application of digital technology, the challenges of consent protocols, direct-to-patient models, and many other attributes must all be considered.